How many units of semaglutide is 0.25 mg?

10 units with a 2.5 mg/mL vial. The answer depends on the strength of your vial: 0.25 mg is 5 units at 5 mg/mL and 25 units at 1 mg/mL, always on a U-100 insulin syringe.

How many units of semaglutide is 2.4 mg?

96 units with a 2.5 mg/mL vial (0.96 mL). At 5 mg/mL it is 48 units. Check the strength on your label and use the calculator above for your exact vial.

How do I convert semaglutide mg to units?

Divide your dose in mg by the vial strength in mg per mL to get mL, then multiply by 100, because on a U-100 syringe 100 units are 1 mL. For example 0.25 mg ÷ 2.5 mg/mL = 0.1 mL = 10 units.

How do I convert semaglutide units to mg?

Divide the units by 100 to get mL, then multiply by the vial strength in mg per mL. For example 10 units from a 2.5 mg/mL vial is 0.1 mL × 2.5 = 0.25 mg.

What size syringe should I use for semaglutide?

One that holds your whole dose in a single draw. A 0.3 mL (30 unit) syringe has the finest scale and suits small doses, a 0.5 mL (50 unit) syringe suits most doses, and a 1 mL (100 unit) syringe holds the most but its lines are usually 2 units apart. Ask your pharmacist which one matches your dose.

What does a unit mean on an insulin syringe?

A unit on a U-100 insulin syringe is a measure of liquid, not of medicine: 1 unit is 0.01 mL. How much medicine those units hold depends on how strong the liquid in your vial is, which is why the same dose can be a different number of units with a different vial.

Why did my units change with a new vial?

Compounded vials come in different strengths, and a pharmacy can change the strength from one order to the next. A stronger vial needs fewer units for the same mg. Check the strength on every new label and work out your units again before you draw.

Do I need this calculator if I use a pen?

Usually not. A prefilled pen gives a set dose, so there is nothing to convert. You need the calculation when your medication comes in a multi-dose vial that you draw up with a syringe, which is how most compounded medication is supplied.

Is this calculator medical advice?

No. It only converts the dose you were prescribed into units for your syringe. Your prescriber decides the dose and when to change it, and your pharmacist can check your first draw with you.

Free, no sign up · Updated October 2026

Semaglutide dosage calculator

See how many units of semaglutide to draw for your dose. Made for compounded semaglutide vials: enter the strength from your label and your dose in mg, and get the units on a U-100 insulin syringe.

Taking tirzepatide? Use the tirzepatide dosage calculator

Vial strength, from the label

mg/mL

Your dose, as prescribedmg

If your prescriber split your dose into more than one injection, enter the mg for one injection.

Your syringe (U-100)

Draw up to

10units on a U-100 syringe

Liquid: 0.1 mL
Dose: 0.25 mg
Strength: 2.5 mg/mL

A conversion, not medical advice. Use the dose your prescriber gave you, check the strength on every new vial, and confirm your first draw with your pharmacist.

The short answer

How to convert semaglutide mg to units

Divide your dose in mg by the vial strength in mg per mL, then multiply by 100. With a 2.5 mg/mL vial, a 0.25 mg dose of semaglutide is 0.1 mL, which is 10 units on a U-100 syringe. The strength on your label decides the answer, so the same dose can be a different number of units from one vial to the next.

To go the other way, from units to mg, divide the units by 100 and multiply by the vial strength: 10 units of a 2.5 mg/mL vial is 0.25 mg.

Dosage chart

Compounded semaglutide dosage chart in units

Units to draw on a U-100 insulin syringe for each approved weekly dose of semaglutide, from 0.25 mg to 2.4 mg, at three common vial strengths. Find your dose in the left column and the strength from your label along the top.

Semaglutide mg to units on a U-100 insulin syringe, by vial strength.
Dose	1 mg/mL vial	2.5 mg/mL vial	5 mg/mL vial
0.25 mg	25 units (0.25 mL)	10 units (0.1 mL)	5 units (0.05 mL)
0.5 mg	50 units (0.5 mL)	20 units (0.2 mL)	10 units (0.1 mL)
1 mg	100 units (1 mL)	40 units (0.4 mL)	20 units (0.2 mL)
1.7 mg	170 units (1.7 mL)	68 units (0.68 mL)	34 units (0.34 mL)
2.4 mg	240 units (2.4 mL)	96 units (0.96 mL)	48 units (0.48 mL)

The doses are the approved weekly strengths, listed only to show the conversion. Follow the dose and the schedule your prescriber gave you. If your vial has a different strength, use the calculator above.

Before you draw

Four checks that prevent a wrong dose

The FDA has reported overdoses with compounded semaglutide, many from mixing up mg, mL and units.

Read the strength on every vial

A new vial can be stronger or weaker than the last. Work out your units again whenever the label changes.

mg, mL and units are different

mg is the medicine, mL is the liquid, units are lines on the syringe. Your prescription is in mg.

Use a U-100 syringe

The units here are for U-100 insulin syringes, where 100 units are 1 mL. Pick a size that holds your whole dose.

Check your first draw

Ask your pharmacist or prescriber to confirm the units the first time, and after any change of dose or vial.

On a GLP-1

Eat enough protein while the weight comes off

With less appetite it is easy to eat too little protein and lose muscle along with fat. The protein calculator sets a daily target that accounts for GLP-1 use, and Protein Buddy helps you hit it in small meals. Taking tirzepatide? Use the tirzepatide dosage calculator.

Check our sources

Research and guidance

FDA alert on dosing errors with compounded semaglutideOverdoses from mixing up mg, mL and units, and how to avoid them.
FDA concerns with unapproved GLP-1 drugsWhat to know about compounded GLP-1 medication.
GLP-1 nutrition advisoryProtein and nutrition during GLP-1 treatment.

Frequently asked questions

How many units of semaglutide is 0.25 mg?: 10 units with a 2.5 mg/mL vial. The answer depends on the strength of your vial: 0.25 mg is 5 units at 5 mg/mL and 25 units at 1 mg/mL, always on a U-100 insulin syringe.
How many units of semaglutide is 2.4 mg?: 96 units with a 2.5 mg/mL vial (0.96 mL). At 5 mg/mL it is 48 units. Check the strength on your label and use the calculator above for your exact vial.
How do I convert semaglutide mg to units?: Divide your dose in mg by the vial strength in mg per mL to get mL, then multiply by 100, because on a U-100 syringe 100 units are 1 mL. For example 0.25 mg ÷ 2.5 mg/mL = 0.1 mL = 10 units.
How do I convert semaglutide units to mg?: Divide the units by 100 to get mL, then multiply by the vial strength in mg per mL. For example 10 units from a 2.5 mg/mL vial is 0.1 mL × 2.5 = 0.25 mg.
What size syringe should I use for semaglutide?: One that holds your whole dose in a single draw. A 0.3 mL (30 unit) syringe has the finest scale and suits small doses, a 0.5 mL (50 unit) syringe suits most doses, and a 1 mL (100 unit) syringe holds the most but its lines are usually 2 units apart. Ask your pharmacist which one matches your dose.
What does a unit mean on an insulin syringe?: A unit on a U-100 insulin syringe is a measure of liquid, not of medicine: 1 unit is 0.01 mL. How much medicine those units hold depends on how strong the liquid in your vial is, which is why the same dose can be a different number of units with a different vial.
Why did my units change with a new vial?: Compounded vials come in different strengths, and a pharmacy can change the strength from one order to the next. A stronger vial needs fewer units for the same mg. Check the strength on every new label and work out your units again before you draw.
Do I need this calculator if I use a pen?: Usually not. A prefilled pen gives a set dose, so there is nothing to convert. You need the calculation when your medication comes in a multi-dose vial that you draw up with a syringe, which is how most compounded medication is supplied.
Is this calculator medical advice?: No. It only converts the dose you were prescribed into units for your syringe. Your prescriber decides the dose and when to change it, and your pharmacist can check your first draw with you.